The Naked Mole Rat: The Key to Increasing the Human Life-span?

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The naked mole rat (Heterocephalus glaber)  is an unappealing un-cuddly subterranean rodent with wrinkled hairless skin, virtually blind, and large sharp curved upper and lower incisors. It lives all its life below the surface of the earth, has never seen or felt the sun, and often lives in toxic conditions with the sort of lack of oxygen and CO2 concentrations that would kill all other mammals.

For its size, its life-span should be 2-3 years.  For all other mammals the life size is related too size, so the bigger the mammal the longer they live- ergo elephants and whales. But the mole rat lives to a ripe old age of 30 plus. Not only that, a mole rat has never been found that has had cancer, and is almost impervious to disease. It also doesn’t age. A 6 month old Mole Rat looks no different from one in its final year. It is also impervious to pain.

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Scientists are studying the mole rat to see if they can find anything in its make-up, DNA, life-style, diet or lack of exposure to the outside world that makes it such a survivor. If the replication of the naked mole rat characteristics could be harnessed and applied to humans we could expect to live up to 6 times longer than now, without ageing- that’s nearly 500 years!

One just hopes that it doesn’t require us to shave all our skin every day,  live underground, and feed on a  diet of plant tubers!

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